Bixori 90 2018-06-04T10:33:00+00:00

Bixori-90 tablet contains etoricoxib. It is a selective COX-2 inhibitor. Cyclo-oxgenase-2 inhibitor plays a major role in joint inflammation and pain. Etoricoxib produces its pharmacological action by inhibiting COX-2. It also possesses anti-arthritic property.

  • In acute pain and gout
  • In osteoarthritis
  • Ankylosing spondylitis
  • Chronic low back pain
  • Acute gouty arthritis
  • Acute pain

Once daily

It is a non steroidal anti-inflammatory drug which produces its pharmacological action by inhibiting the isoform 2 of cyclo-oxgenase which is involved in inflammatory process. It inhibits prostaglandin generation from arachidonic acid.

Absorption

After oral administration the drug is 100% absorbed in the body

Distribution

About 90% of the drug is bound to plasma protein. The metabolism of the drug is through liver by CYP3A4.

Excretion

The drug is excreted through urine and feces

  • Hypersensitivity to non steroidal anti-inflammatory drug
  • Peptic ulcer
  • Inflammatory bowel disease
  • Severe congestive heart failure
  • Pregnant patients
  • Patients with allergic disorders
  • Renal impairment
  • Cardiac diseases
  • Hepatic impairment
  • In geriatrics patients