D3HP Sachet contains Cholecalciferol. It is also called as vitamin D3. Vitamin D3 is the raw form of the nutrient which we get from sunlight. It is the form of nutrient which is processed by the body for its use. It is mainly used for the calcium in the body to have strong bones and teeth.
- Maintenance of bone health
- Treatment of bone disorder like osteomalacia, rickets
- Maintains low level of vitamin D in the body
One capsule once daily
The vitamn D3 after administration produces its action by getting activated by hydroxylation . The activation of vitamin D3 causes binding to the receptor which work as a transcription factor for modulation of gene expression. It forms complex with the respective receptor and causes binding to DNA. It usually activates the transcription. It increases the serum calcium absorption through GI and also by distal tubular reabsorption. The absorption of calcium depends on calcium binding protein.
Absorption
After oral administration it is readily absorbed from the body
Distribution
About 50-80% of the drug is bound to plasma protein. The metabolism of the drug takes place through liver. By the help of enzyme 25-hydroxlase the drug gets hydroxlated to calcidol i.e 25-hydroxycholecalciferol. The half life of the drug takes several weeks.
Elimination
The drug is excreted through renally and by biliary excretion.
- Hypersensitivity to drug
- Don’t take medicine unless it is prescribed by doctor
- Only use supplements when clearly required or advised