Eclogesic SR 2018-06-04T10:55:43+00:00

Eclogesic SR contains Aceclofenac in sustained release form. It is a phenylacetic acid derivative which produces its action on inflammatory mediators. It is a glycolic acid ester of diclofenac.

  • Ankylosing spondylitis
  • Rheumatoid arthritis
  • Osteoarthritis

Once daily

Aceclofenac

It is a NSAID which produces its action by blocking COX-1 which is involved in inflammatory processes. This inflammatory mediators produces response to any injury and cause pain and swelling. It is a glycolic acid ester of diclofenac.

Aceclofenac

Absorption

After oral administration it is well absorbed in the body.

Distribution

About 99.7% of the drug is bound to plasma protein. It produces its action  by concentrating in synovial fluid. The drug is metabolized in liver as 4-hydroxyaceclofenac.

Excretion

It is excreted as conjugated metabolites through urine.

  • Hypersensitivity to any of the component present in the drug
  • Patients with asthma, bronchospasm or acute rhinitis
  • Renal impairment
  • Patient with the history of peptic ulcer
  • Cautiously used in epileptic patients and patients  with convulsions
  • Lower dose should be used in patients with diarrhea
  • Ulcerative colitis
  • Crohn’s disease
  • Elderly Patients